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SKU: PP17236

AM/PM PeriMenopause Formula relieves the symptoms of perimenopause. Most women typically enter perimenopause during their mid 30's to late 40's. Symptoms are similar to menopause, including hot flashes, lack of energy and night sweats.*

Benefits
•AM Formula relieves hot flashes, lack of energy, irritability, and mood swings*
•PM Formula relieves occasional sleeplessness, hot flashes, and night sweats*

Key Features
•Studied dosage of standardized black cohosh
•More powerful than black cohosh alone*

How Does It Work?

AM Formula:

Black Cohosh
Black cohosh has long been used to support female health, and continues to be widely used to relieve the symptoms of perimenopause. Black cohosh has been shown to be effective in relieving daytime hot flashes and night time sweats. About 75% of women experience mild or moderate hot flashes while 15% will have severe hot flashes. These hot flashes can lead to embarrassing situations, physical discomfort and psychological stress. Night sweats may lead to interrupted sleep; lack of sleep can cause daytime moodiness and irritability. In clinical trials, the occurrence of hot flashes while taking black cohosh decreased from an average of 4.9 per day down to an average of less than one per day. Additional research studies have also shown black cohosh's effectiveness on the many perimenopausal symptoms in addition to hot flashes and night sweats.*

Because of the effectiveness in relieving perimenopausal symptoms such as irritability and mood swings, black cohosh was originally believed to have a hormonal-like action. Though the exact mechanism of action has not been clearly defined, recent studies have found black cohosh to have no estrogenic action. It is now theorized that the action of black cohosh is a more central, dopaminergic like action. This theory postulates a link between serotonin receptors and the hypothalamus. Results of clinical studies suggest that adverse effects from black cohosh are mild and infrequent.*

Green Tea
Green tea has long been known for its positive effect on energy. It has also been suggested that green tea has thermogenic effects, which have proven helpful in controlling body weight, a concern of the perimenopausal woman. Green tea is well established as a potent source of antioxidants. Green tea contains the antioxidant known as epigallocatechins – gallate (EGCG). Recent studies have shown that EGCG promotes the growth of healthy cells. Studies additionally have specifically shown that green tea supports healthy breast tissue. The exact mechanism is unknown, but theories include acting as an antioxidant and inhibiting enzymes involved in cell replication and DNA synthesis, by interfering with cell-to-cell adhesion, or by inhibiting some of the intracellular communication pathways required for cell division.*

Chaste Tree Berry
Chaste tree berry, although it contains no hormones, supports healthy progesterone levels. Research has found that this effect is due to chaste tree's stimulation of the pituitary gland. The pituitary gland secretes luteinizing hormones, which in turn signal the ovaries to produce more progesterone. A balance between estrogen and progesterone relieves the symptoms of estrogen dominance. In clinical trials, no significant adverse effects were associated with the use of this herb. In a survey of perimenopausal women using chaste tree berry extract, 94% rated the beneficial effect as good or very good.*

Rhodiola
Rhodiola is native to mountainous regions and has long been used as a healing herb. Its most well known uses are to help combat fatigue and restore energy. Notably, rhodiola is well documented as an adaptogen (an endurance enhancer). In this capacity it helps the body stay healthy and perform at its best despite physical exhaustion or environmental stressors. Preliminary research indicates that rhodiola's benefits occur through influencing key chemicals in the central nervous system. It is believed that rhodiola affects neurotransmitters in multiple neuronal pathways. Still other studies show that rhodiola benefits learning capacity, memory enhancement and increased capacity for work and endurance. The level of mental fatigue (short term memory, associative disorder, and audio-visual perception) was much reduced after supplementation with a rhodiola supplement compared to the placebo group in a double blind study.*

PM Formula:

The PM formula is designed with ingredients to support a relaxed state that allows restful sleep while not causing morning grogginess.*

Valerian
Valerian is a key ingredient in the PM formula, which targets the need for good quality sleep while going though this “change of life” transition. Valerian (Valeriana officinalis) has been reported to have sleep inducing and calming effects in laboratory studies and clinical trials. A placebo-controlled, crossover trial of 128 volunteers reported that 400 mg of valerian extract at bedtime led to improved sleep quality, decreased sleep latency, and reduced the number of night awakenings. Two other clinical studies using 400-900 mg valerian before bedtime also demonstrated improved sleep quality. In a double-blind, cross-over, placebo-controlled trial, subjective sleep latency and wake time after sleep-onset were reduced by more than half after a 900 mg dose, with a smaller effect after 450 mg. One electroencephalographical (EEG) study reported that 135 mg of aqueous, dried extract of valerian, taken three times daily, improved delta sleep and decreased stage 1 sleep.*

In general, clinical studies with valerian extracts suggest that the mild sleep-inducing effect of valerian decreases sleeps latency and improves sleep quality. Research has shown a subjective improvement in the sleep experience when taken nightly over one to two week periods.*

Hops
Hops flowers have long been successfully used for their soothing and calming effect. Although it has a long history of use for gastrointestinal support, recent interest has focused on the ability of hops to support restful sleep. Key constituents of hops include a volatile oil, valerianic acid, phytoestrogenic substances, tannins, and flavonoids. Hops have been demonstrated to induce sleep.*

L-Theanine
L-theanine is considered a unique amino acid that is found in tea plants and thought to contribute to the “exotic” taste of green tea. Research has shown that in addition to its flavor properties, L-theanine also has a relaxing effect. L-theanine does not contain caffeine and actually acts antagonistically on the side effects of caffeine. It is believed that after being absorbed in the large intestine, it stimulates the generation of alpha waves in the brain. Alpha waves are associated with a calm and relaxed state. L-Theanine reduces stress, promotes relaxation without drowsiness, eases nervousness due to common every day overwork and fatigue, and reduces nervous irritability.*